Streptozocin is a drug approved by U.S. Food and Drug Administration (USFDA) for the treatment of pancreatic islet cells cancer. Streptozocin is classified as an alkylating agent, which produces anti-cancer effects by causing a chemical reaction that damages the DNA in a cell. The DNA damage caused by streptozocin results in the cell death. Streptozocin damages pancreatic cells causing hyperglycemia, so, also used in medical research to produce an animal model for hyperglycemia.
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Increasing research activities using streptozocin is expected to propel growth of the streptozocin market during the forecast period. For instance, an article published in the journal Nature in February 2018, stated that streptozocin may reduce the virulence of Staphylococcus aureus. It is a Gram-positive human pathogen, which colonizes at skin and other mucosal surface and causes various diseases ranging from skin and soft-tissue infections, endocarditis, toxic shock syndrome, and necrotizing pneumonia. The virulence gene in the bacteria can be targeted by streptozocin.
Shortages of streptozocin in the global market during the forecast period my affect the growth of streptozocin in global market. For instance, according to Drug Shortages of Canada in March 2017, Zanosar sterile powder for solution manufactured by PALADIN LABS INC., containing streptozocin was on shortage in 2017. The drug was manufactured by Furthermore, rising prevalence of kidney diseases are negatively inhibiting the growth of streptozocin in global market since streptozocin is contraindicated in the kidney diseases due to renal toxicity. For instance, according to national Institute of Diabetes and Digestive and Kidney Diseases, of U.S., in 2015, overall prevalence of Chronic Kidney Disease (CKD) in the general population in U.S. was around 14 percent in 2015, which my hamper growth of the streptozocin market.
Key players operating in streptozocin market include Sigma-Aldrich, Inc., LGM Pharma., Xiamen Hisunny Chemical Co Ltd, Beijing Yunbang Biosiciences Co Ltd, Neostar United Industrial Co Ltd, Haihang Industry Co Ltd, Shaanxi Top Pharm Chemical Co Ltd, and Chengdu Yuyang High-Tech Developing Co Ltd.
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